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Check out the latest from Astral Codex Ten, Stratechery, Peter Zeihan, Slow Boring, Noahpinion.

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Latest stories

What Not to Ask Me About My Long COVID [Jennifer Senior, The Atlantic]

W

• Long COVID is a condition that millions of people suffer from, and it is often worse than the physical symptoms.
• Asking “Are you doing any better?” is not helpful, as it is a chronic illness with an unknown recovery timetable.
• People with long COVID often experience depression, shame, and resentment.
• To pass for well, people with long COVID may need to take a combination of medications.
• Doctors often underestimate the quality of life issues associated with long COVID.
• The Mount Sinai Hospital in New York has a long-COVID team that thinks holistically, but many people don’t have access to the same resources.
• Be gentle with people who have long COVID, as it can be a difficult and isolating experience.

Published February 15, 2023
Visit The Atlantic to read Jennifer Senior’s original post What Not to Ask Me About My Long COVID

Peter Zeihan – Next on the Chopping Block: Moldova [Peter Zeihan, Zeihan on Geopolitics]

P
  • Moldova is a small country located between the Carpathian Mountains and the Black Sea that has been used as a training ground for Russian intelligence agencies.
  • The Russians have used their political influence in the country to engineer the fall of the government.
  • Whoever controls Moldova has been able to determine which way the armies can flow.
  • The Eastern edge of Moldova, called Transnistra, declared independence in 1992 with Russian sponsorship and has maintained independence ever since.
  • Russia has maintained a strong presence in the country and has worked to make sure that the government of Moldova is as non-functional as possible.
  • During the Ukraine war, Russia has tried to use Moldova as a wedge either to manipulate refugees coming out of Ukraine or to launch missiles into Ukrainian targets.
  • If Ukraine falls, Moldova is the next target.
  • If Ukraine wins, Ukrainian or NATO military action against the Russian troops in Transnistra could fold Moldova into the European and the NATO family of countries.

Published February 15, 2023

Visit YouTube to read Peter Zeihan’s original vlog Peter Zeihan – Next on the Chopping Block: Moldova

February 14, 2023 [Heather Cox Richardson, Letters from an American]

F

• On Valentine’s Day in 1884, Theodore Roosevelt lost both his wife and his mother.
• Four years before, Roosevelt had married Alice Hathaway Lee and they had a daughter.
• Alice was suffering from Bright’s Disease and his mother from typhoid.
• Roosevelt escaped to Dakota Territory to become a rancher, but his cattle died in a brutal winter.
• He returned to politics with a cowboy image and eventually became President of the United States.
• As President, he worked to clean up the cities and stop the exploitation of workers.

Published February 15, 2023
Visit Letters from an American to read Heather Cox Richardson’s original post February 14, 2023

Yes, Elon Musk created a special system for showing you all his tweets first [Zoë Schiffer, Platformer]

Y

• Elon Musk’s tweet about the Super Bowl got less engagement than President Joe Biden’s, prompting Musk to fly back to the Bay Area to demand answers from his team.
• Engineers worked through the night to investigate why Musk’s tweets weren’t performing as well as they should.
• They discovered that Musk had been blocked and muted by many people, and that Twitter’s system had been promoting other users’ tweets over his.
• To fix the issue, they deployed code to automatically “greenlight” all of Musk’s tweets, boosting them by a factor of 1,000 and bypassing Twitter’s filters.
• This caused an uproar, and Musk acknowledged it with a meme. The artificial boosts remain in place, although the factor is now lower than 1,000.
• The incident highlights the tension between why some posts are more popular than others, and the difficulty of understanding why people see certain things and not others.
• Google previewed Privacy Sandbox, its answer to Apple’s App Tracking Transparency.
• Instagram will shut down its live shopping feature in March.
• Meta updated the “Why am I seeing this ad?” feature on Facebook to include information about how the company uses machine learning to analyze users’ behavior.
• Andy Jassy says Amazon is doubling down on the company’s grocery store business despite slow growth.
• Spotify removed a clause that let Apple use human voices from Findaway Voices to train Apple’s machine-learning systems.
• Twitter and other big companies are cutting Slack and Salesforce contracts.
• The NFT market been inching back up, with sales on the ethereum blockchain jumping from $546.9 million in December to $780.2 million in January.
• BuzzFeed launched “infinity quizzes,” letting users build personalized narratives using technology from OpenAI.

Published February 15, 2023
Visit Platformer to read Zoë Schiffer’s original post Yes, Elon Musk created a special system for showing you all his tweets first

‘They Didn’t Understand Anything, but Just Spoiled People’s Lives’ [Nataliya Gumenyuk, The Atlantic]

• The Reckoning Project has collected evidence of war crimes in Ukraine, including the targeting of local officials for interrogation and torture.
• Viktor Marunyak, mayor of Stara Zburjivka, was arrested and tortured by Russian soldiers, who seemed to have no clear understanding of why they were occupying Ukraine.
• Other mayors, deputy mayors, and local leaders from the Kherson region were also arrested or kidnapped, and some have disappeared.
• Russian forces have replaced elected officials with random, unqualified people, and have displayed Soviet symbols in an attempt to gain sympathy.
• Volunteers who run charities and civic organizations have also been targeted, as the Russians seem unable to believe that people are spontaneously helping each other.
• Two volunteers, who requested anonymity, were interrogated and beaten, and asked repeatedly about a nonexistent conspiracy.
• The Russian occupiers of Ukraine have been haphazardly attempting to Russify the educational system, with little success.
• They have removed Ukrainian-language books from some schools, imposed a Russian-language curriculum, and forced some teachers to return to work.
• The occupiers have also resorted to violence, including beatings, electric shocks, and arbitrary arrests.
• This violence is rooted in the occupiers’ frustration with their own incapacity to control the Ukrainians, and their incomprehension of Ukrainian culture.
• The occupiers’ actions are reminiscent of the Potemkin village legend, and are part of a larger tradition of Russian imperialism and Soviet genocide.
• Despite the occupiers’ attempts to destroy Ukrainian society, the Ukrainians remain resilient and determined to resist.

Published February 14, 2023
Visit The Atlantic to read Nataliya Gumenyuk’s original post ‘They Didn’t Understand Anything, but Just Spoiled People’s Lives’

Ro-mantic Monday 2/13/23 [Scott Alexander, Astral Codex Ten]

R

• This installment of Mantic Monday focuses on attempted clever engineering solutions to romance.
• Date Recommendation Markets: Aella created a prediction market to find a partner.
• Matching Checkbox Sites: People can check off the people they would like to date and send it to a central database.
• Alas, Poor Luna: A cryptocurrency dating site that failed due to lack of women signing up.
• What Can Peter Thiel Teach Us About Dating?: Chicken-and-egg problem for social startups.
• This Week In The Markets: A prediction market about how many cold approaches a bit-more-desirable-than-average guy needs.
• Short Links: Justin Murphy offered arranged marriages to his followers, and a programmer fell in love with a chatbot.

Published February 14, 2023
Visit Astral Codex Ten to read Scott Alexander’s original post Ro-mantic Monday 2/13/23

Will CRISPR Cure Cancer? [Brian Gallagher, Nautilus]

W

• Brad Ringeisen, chemist and executive director of the Innovative Genomics Institute, is working on two approaches to deliver CRISPR-Cas9 treatment to target cancer cells.
• The first approach is to use antibodies to bind to something that’s only found on a specific cell type.
• The second approach is to use envelope delivery vehicles, which take certain parts of a virus’ targeting system to help specifically target a certain cell type or tissue type.
• Intellia Therapeutics has already shown that CRISPR-Cas9 treatment can be applied intravenously to treat a liver disease.
• The dream is to do an infusion and then monitor the patient for a day or two, as this would be the most efficient and successful way to treat cancer with CRISPR-Cas9.

Published February 14, 2023
Visit Nautilus to read Brian Gallagher’s original post Will CRISPR Cure Cancer?

Peter Zeihan – How Stable Is the Russian Oil Industry? [Peter Zeihan, Zeihan on Geopolitics]

P
  • Russian oil production – 500,000 barrels/day, 1/2 of 1% of global production, 10% of Russian exports
  • Permafrost – Damage to wells takes 30 years to repair, without oil services firms
  • European oil & refined products ban – Reduces demand for Russian product, break-even price for Russian crude is between $40 & $60/barrel
  • Friday seminar – Covers economic impacts of war one year out, including oil & disruptions, natural gas, raw Commodities, Agriculture, & entire supply chain

Published February 14, 2023

Visit YouTube to read Peter Zeihan’s original vlog Peter Zeihan – How Stable Is the Russian Oil Industry?

Contra Kavanagh On Fideism [Scott Alexander, Astral Codex Ten]

C

• Chris Kavanagh recently tweeted about Scott Alexander’s article on Ivermectin, criticizing the rationalist community for ignoring conspiracy ecosystems and how they distort things.
• Rachel responded to Chris’ tweet, suggesting that the article may have persuaded some people to get vaccinated instead of taking Ivermectin.
• Chris responded to Rachel, saying that his critique was orientated towards the rationalist community and what it says it does vs. what he sees.
• The author shares a personal story of how he was once a believer in a conspiracy theory, and how anti-conspiracy bloggers and podcasters could have saved him from a five year wild-goose-chase, but chose not to.
• Kavanagh’s criticism of the author’s 25,000 word essay on ivermectin is accepted, but not from him, as he has devoted his career to the subject.
• The author interprets Kavanagh’s comment as suggesting that it is a mistake to even try to evaluate the evidence, as it suggests there might be evidence on both sides.
• The author points out that there were actually thirty different studies that supported ivermectin, and it was adopted in several countries.
• The author compares Kavanagh’s comment to fideism, the belief that someone who reasons their way to belief in God is a sinner.
• The author argues that the PR argument of Kavanagh’s comment looks bad, as it suggests that doing good science is a near occasion of sin for doing bad science.
• The author argues that conspiracy theorists have the same biases as everyone else, but are slightly worse at applying CONSTANT VIGILANCE.
• The author uses the example of premenstrual dysphoric disorder to illustrate how it is not obvious how to apply the heuristic “trust experts”, and how both sides were trying to make the reader short-circuit their thought process.
• The author argues that it is important to have tolerance for others forming their own opinions, and for science communicators to help guide people through this process.

Published February 15, 2023
Visit Astral Codex Ten to read Scott Alexander’s original post Contra Kavanagh On Fideism

If Technology Only Had a Heart [Sian E. Harding, Nautilus]

I

• The history of the total artificial heart is punctuated with both brilliant innovation and continual clinical failure.
• In 1964, President Lyndon B. Johnson funded a program to develop the first functional self-contained artificial heart.
• The first total artificial heart was implanted in 1969, but a reliable off-the-shelf version is still out of reach.
• The original goal was to replace the failing heart completely, but the goal changed to keeping the patient alive until a transplant donor could be found.
• The development of ciclosporin in the early 1980s dramatically improved the success of heart transplantation.
• Ventricular assist devices (VADs) take blood out of the ventricle of the heart and push it into the aorta at high pressure.
• Left ventricular assist devices (LVADs) have become a therapy in themselves, with survival rates of over 50 percent seen at seven years.
• Solutions for a completely implantable total artificial heart seem tantalizingly close, but no one is anticipating an easy ride.

Published February 14, 2023
Visit Nautilus to read Sian E. Harding’s original post If Technology Only Had a Heart

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